In her 30-year career, Madonna inspired enough people in the mainstream to more than earn her Queen of Pop title.
More than that though, her influence has spread like a spider web into the wider (and weirder) world of music.
To celebrate her latest release, we've thumbed through our dusty record collection for ten of the stranger Madonna covers from the last three decades.
Ciccone Youth: 'Into The Groove(y)'
Perhaps the ultimate in weird Madonna. Sonic Youth team up with Mike Watt for a scuzzy grunge take on Madonna's Desperately Seeking Susan hit before the Queen steps back into the room.
Kelly Osbourne: 'Papa Don't Preach'
We can't imagine Kelly's Papa Ozzy preaching at her if she got knocked up, if we're being honest, but we still enjoy this thrashy, shouty punk-pop take on the True Blue classic.
Bernholz: 'Austerity Boy'
Not strictly a cover, more a Madge-inspired wundertrack that turns the original on its head before revealing its source material, but we like it so much we couldn't leave it off this list.
Teenage Fanclub: 'Like A Virgin'
The Scottish indie band at their most shoegazing take on one of Madonna's biggest hits in this cover from their second album The King.
The Flaming Lips: 'Borderline'
After slipping the odd remarkable cover into their live sets over the years, The Flaming Lips' best work these days comes when they deconstruct tracks and complete albums from other artists.
Heaven 17: 'Holiday'
A track from the first volume of the weird-cover packed Virgin Voices - A Tribute To Madonna.
KMFDM: 'Material Girl'
... and an almost-unrecognisable industrial smash-up from volume two.
My Vitriol: 'Oh Father'
A B-side from the band's biggest hit 'Grounded'. The band reformed a few years back but we're still awaiting a follow-up to 2001 debut Finelines
Sigue Sigue Sputnik: 'Ray Of Light'
From ex-Generation X-er Tony James's New Wave band's 2007 Ray Of Light covers EP
Russia's ever-prolific DDT covered Madge's fashion-tastic track on their 1993 album Discomedia
What is your favourite cover of a Madonna song? Let us know in the space below.