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The police received a tip-off from local residents that the three-bedroom family home was suspected of housing a cannabis factory.
On a series of raids on other nearby properties police found a poisonous king cobra, three monocled cobras and a rattlesnake, Metro reports.
Cheshire Police's Inspector Dave Gordon said that some of the animals seized were "potentially lethal", adding: "We were concerned for the safety of the public, so swift action was taken."
Specialist reptile handlers dealt with the animals and removed them to a safer place.
A 33-year-old man was arrested on suspicion of cultivating cannabis, abstracting electricity and possessing dangerous wild animals.
He has since been released on police bail but the investigation continues.
> Crocodile found by family in lounge
> Duo arrested for stealing 260 baby alligators
