Rex Features
The Spirit actress revealed that she had caught a cold from co-star Samuel L. Jackson when she appeared on The Tonight Show With Jay Leno.
The 24-year-old joked that her germs probably had some value, so when she blew her nose with the tissue and left it behind, NBC bosses decided to auction it for charity.
The tissue is now listed on eBay and has already attracted bids of over $2,000 (£1,292).
All proceeds will go to USA Harvest, the largest volunteer feeding organisation in America.
