The actress, who co-stars with Clooney in the rom-com Up In The Air, has insisted that she loved working with the actor, STV reports.
The 36-year-old said: "George has been breaking women's hearts for years. It's fun to turn the tables. But it's disgusting how much charm he has. He oozes it."
Farmiga, who had given birth to her son before filming began, has admitted she wasn't pressured into shooting a nude scene.
She added: "Oh, those weren't my buttocks. It wasn't appropriate to be naked because I was breastfeeding every 20 minutes."