The former Baywatch actress will appear as the Genie in a celebrity-packed performance of Aladdin, a role that she played last year in London.
Anderson will be joined by former Family Fortunes host and panto regular Les Dennis, as well as Happy Days star Henry Winkler, who came to Liverpool last year to play Captain Hook in Peter Pan.
"I was thrilled to be invited to play the Genie again," Anderson told The Sun. "I'm really going to have a great time.
"It's fun, tongue-in-cheek and a cool experience for kids and adults, especially those just beginning their theatre life."