Simon Cowell's ex-girlfriend said that she was diagnosed as a teenager but felt that the condition had made her appreciate her life even more.
The 36-year-old said: "When I was an 18-year-old model, I developed lupus. I was in terrible pain and had to be put on a cocktail of drugs. I have been in remission for years."
According to The Sun, she added: "It's made me much more aware of my own mortality."
Lupus is a disorder which causes the body's immune system to attack its own cells, leading to tissue damage and inflammation.
Lady GaGa recently tested "borderline positive" for the disease.