Arquette called The Howard Stern Show this afternoon and shared intimate details of his separation with Cox, admitting that he had slept with someone else since the couple had parted ways.
According to TMZ, Arquette explained that he and Cox had not had sex since soon after their 11th wedding anniversary in June, when the 42-year-old actress told him she was "tired of being [his] mother".
He added that he was working on trying to "grow up" by going to therapy, saying: "I'm trying to be my true self."
The actor also said that while he had not cheated on Cox, he had slept with former cocktail waitress Jasmine Waltz since the split.
"I did have sex with her one time, maybe twice," Arquette revealed. "My sexual encounter made me feel pretty manly."
Despite the separation, Arquette further said that his estranged wife is "the greatest woman I've ever met" and that he hopes they can reconcile.