The Boston Celtics forward made his orchestral debut at the city's famed Symphony Hall on Monday night.
The athlete told ESPN that he was prompted to accept the one-night-only gig by the Celtics' front office.
"[Celtics PR director Heather Walker] asked me if I wanted to conduct the orchestra," he said. "I was like, 'Seriously, like a real orchestra?'"
O'Neal's set with the Boston Pops included interpretations of Queen's 'We Are The Champions', the Jackson 5's 'Can You Feel It', and the seasonal standard 'Sleigh Ride'.
The basketball player further commented: "I have a whole new respect for conductors."
The Boston Pops Orchestra held its inaugural concert in 1885 and has since hosted famed conductors Keith Lockhart, John Williams, and Josef Pasternak.