The AP reports that the Moulin Rouge star will bring his 'Ghetto Clown' show to New York City's famed Lyceum Theater.
'Ghetto Clown' is to continue on the heels of previous stage shows Spic-O-Rama, Freak and Sexaholix, all of which covered different periods in the comedian's life.
Acclaimed theater director Fisher Stevens is to be helming Leguizamo's newest offering.
This New York mounting of 'Ghetto Clown' will mark the actor's fifth Broadway sojourn, after most recently starring in a 2008 production of David Mamet's American Buffalo.
'Ghetto Clown' is to kick off its 12-week run on March 22.