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However, the 30-year-old actor insisted that he has more important endeavours, seemingly referring to his girlfriend, country singer Taylor Swift.
He told PA: "I think casual sex some people are into, I definitely have been in my life at times. I think you find other things more important as time goes on."
Promoting new movie Love And Other Drugs, in which he stars alongside Anne Hathaway, Gyllenhaal added: "I feel people might be tired of the normal clichéd typical movie and so we put our minds together and I think we raised the stakes.
"We decided it was going to be two characters that both really couldn't be intimate and so we both went to sex as a way of avoiding things. The movie does start off with the two of them sort of primal and animalistically having sex."
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