French magazine VSD ran an online poll where 1,713 people were quizzed on their least favourite celebrities, sports stars and politicians. Bruni, who recently completed her first acting role in Woody Allen's upcoming Midnight in Paris, was found annoying by 52% of voters.
Actor Alain Delon was in second place, while Jean de Florette and Hollywood star Gérard Depardieu was third.
Bruni's husband, French President Nicolas Sarkozy, was fourth in the politician vote - as 63% of voters found him annoying.
Allen previously said that he was "delighted" by Bruni's work on Midnight in Paris and didn't find her hard to work with.