The Sex Pistols and Public Image Ltd frontman told The Guardian that he uses a magnified mirror for the pastime.
Lydon said: "When I look in the mirror, I notice spots, blackheads and zits.
"I have a favourite occupation: I love to squeeze 'em. The mirror of choice is magnification to the nth degree. The skin looks like a lunar landscape."
He added: "The real colour of my hair is mouse. I always want to be ginger, which I was when I was born, or blond, because I live in LA, and I want to look like I go surfing without any physical effort.
"My favourite thing is cotton buds - like safety pins, they have a thousand uses. I love to poke them up my snozzle - to get the bits you can't quite blow out."