The 52-year-old actor of St Mary's Road, Garston - who played Terry Sullivan in the Channel 4 soap from 1982 to 1997 - has been accused of shooting Bahman Faraji, 44, outside a pub on February 24, BBC News reports.
Regan was previously arrested by the police on Tuesday over the incident.
Another man, Lee Dodson, 42, of Logfield Drive, Garston, has also been charged with murder. Both men were remanded in custody at Liverpool Magistrates' Court and will appear at Liverpool's Crown Court on April 18. The men did not enter any pleas.
Edward Heffey, 40, of Beloe Street, Dingle, Liverpool, who was charged with murder earlier this month, will also appear at the crown court on the same day.
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