The 'Judas' singer explained that she feels like a "loser kid in high school" because of how she is treated.
In the black and white YouTube clip, posted before she went on stage in New York's Madison Square Garden for her Monster Ball Tour show, she sobbed: "I still sometimes feel like a loser. It's crazy, 'cos it's like we're at the Garden, but I still feel like a loser kid in high school.
"Sometimes I still feel like people are trying to destroy me... I cannot be destroyed and I will not be destroyed. And you will never destroy the kingdom that is my fans."
The 25-year-old insisted that she will "fight" to remain successful for the sake of her fans, adding: "I just have to pick my s**t up, pick myself up and tell myself I'm a superstar every morning just so I can get through this day.
"I feel like I have to fight. I'm fighting for every kid that's like me, that's felt like I've felt and feels like I still feel."
She added: "I just wanna be a queen but sometimes I just don't feel like one. It's not about being a winner for me anymore, you know. It's about being a winner for them."
The clip was filmed as part of documentary Lady Gaga Presents The Monster Ball Tour: At Madison Square Garden, which will be aired next month.
GaGa recently admitted that she has considered having face implants.
Watch Lady GaGa's outburst below: