In March, it was confirmed that production on the musical would shut down for several weeks to implement a number of significant changes, which included several new musical numbers from Bono and bandmate The Edge.
"What was not right about it was a catalogue of commonplace problems," Bono admitted to The New York Times. "Story knots, bad sound, and finally a failure to cohere, meaning that the whole was not greater than the sum of the parts, as wonderful as some of those parts were."
Bono also explained some of the main changes, confirming that the new plot focuses less on the mystical Arachne and more on Spider-Man's traditional role as a superhero.
"In Turn Off the Dark 2.0, the myth of Arachne does not overpower the reason people are there," he said. "To discover what makes Peter Parker a superhero, which in the end turns out not to be his spider senses but his personal integrity and especially his humility."
The critically-panned production has become the most expensive in Broadway history, costing around $70 million (£43m) to bring to the stage.
Spider-Man: Turn Off the Dark is due to reopen to the public on June 14.
> Spider-Man musical to resume this week