The Sex and the City actress previously starred in last year's London staging of Private Lives, which was written by Noël Coward in 1930.
Canadian actor Paul Gross, best known for his work in Due South and The Red Green Show, will star opposite Cattrall.
Private Lives is the comedic tale of a formerly married couple who accidentally meet up at a resort while honeymooning with new partners.
Five-time Olivier Award winner Richard Eyre will direct, while Simon Paisley Day, Caroline Olsson and Anna Madeley have signed on for supporting roles.
Cattrall previously performed on Broadway in the 1986 adaptation of Michael Frayn's Wild Honey.
Private Lives will run from November 17 until February 5, 2012 at New York City's Music Box Theatre.
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Watch Kim Cattrall's curtain call from the London production of Private Lives below: