The Australian actress, who is best known for her roles in Home and Away, Water Rats and Stingers, said that she has had many "dark nights" during her quest to be a success in the US acting industry.
Wilson split from her husband, The Amazing Race host Grant Bowler, last year after almost ten years together. They have 8-year-old daughter Edie and 6-year-old Zeke.
She told the Herald Sun that trying to crack the American market throughout her marriage was "bleak" at times, saying: "You get to a point where you're in so deep and you've stuck at it so long. I found it hard to justify going off and shooting 14-hour days with Grant out of the country.
"I [still] have many dark nights when I go, 'Is this worth it?' If you pursue any dream there's going to be times when you go 'at what cost?' I'm a persistent person, stubborn and determined. There is something about this country that keeps calling me back."
Wilson admitted that when she and Bowler split, "finally things were happening" in his career, adding: "We're not together anymore. That's one of the costs of the journey." She also said that she feels lucky as her acting work is "really flowing" at the moment.
Former Home and Away star Rhys Wakefield revealed earlier this year that he credits the late Heath Ledger with "paving the way" for young Australian actors trying to make it in LA.
Current Summer Bay star Rebecca Breeds has also said that her "plan" is to move to Los Angeles and try and break into the US film market when she feels her time on Home and Away has come to a natural end.