Ifans allegedly pushed a female security guard only moments before his appearance on the Amazing Spider-Man panel, after she refused to let a member of his entourage enter the hall.
While the guard in question allowed him to complete his panel appearance, she performed a citizen's arrest on the actor shortly afterwards.
"He was aggressive and belligerent," Lieutenant Andra Brown told The Wrap following the incident. "He was berating everyone from the security staff to the United States of America.
"He was cited and released, which is a non-custodial misdemeanor arrest."
A San Diego City Attorney will now determine whether or not Ifans will face criminal charges for his behaviour.
Ifans was appearing at Comic-Con to promote Marc Webb's comic book reboot The Amazing Spider-Man, in which he stars as the film's main villain The Lizard.
Yesterday, Ifans claimed that there was no truth to the rumours that he will star opposite Daniel Craig in the long-awaited Bond 23.
Representatives for the actor have yet to comment on his arrest.
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