The 62-year-old, who stars in historical drama The Borgias, shared his belief that females are "robust" enough to withstand potentially offensive forms of "communication".
On the topic of political correctness, he told The Sun: "There are too many people in power with too little to do so they churn out laws to justify their jobs.
"Most people are robust. If a man puts his hand on a woman's bottom, any woman worth her salt can deal with it. It's communication. Can't we be friendly?"
Irons went on to admit that he is regularly advised by his actress wife Sinead Cusack to be less brazen in interviews.
"Sinéad criticises me for being too frank. But that's the only way I can be," he said. "I am what I am and I do what I do."
The Borgias was renewed for a second season by US network Showtime back in April. It will make its UK premiere on Sky Atlantic on August 2.
Watch a behind-the-scenes video from The Borgias below: