The former Guns N' Roses guitarist tweeted that he and Ferrar feel it is important to rededicate themselves to one another after a decade of marriage.
Slash wrote: "Perla & I are renewing our vows later this month in early celebration of our 10 year anniversary. Which is really in Oct."
Perla and Slash wed in Hawaii in 2001 and are the parents to two young sons, 8-year-old London and 7-year-old Cash.
The couple were reportedly on the verge of splitting last summer, but reunited in November 2010.
Slash was previously married to model Renée Suran, but they ended their relationship in 1997 after five years together.
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Watch Slash perform 'Black or White' with Michael Jackson below: