The Hairspray star made the comments while promoting her new fashion line, which launched on the Home Shopping Network this weekend.
"I'd probably give her a pair of my skinny moto jeans and a fresh moto jacket with a cool tank, and I'd probably get her a nice pair of Ralph Lauren boots, throw her on a cool-ass motorcycle and tell her to go," Latifah told People. "But that's just me. I'm standing in New York looking over the city, and I like to see a little ruggedness."
Despite offering fashion advice to the new Duchess of Cambridge, Latifah said she wouldn't change anything about Pippa Middleton's look.
"Pippa's still kind of up-and-coming to me, she should get to wear whatever she wants," Latifah explained. "It's time to experiment with the kinds of things she wears.
"I think she has a great sense of taste, and she seems just like a girl's girl, and she knows how to have fun with the boys."
Latifah was rumoured to have signed on for the new season of Dancing with the Stars, but has since claimed she would be too busy to take part.
A recent survey showed that around 2% of Americans think Pippa Middleton is a porn star.