The Drive star said that since splitting from McAdams in 2008 he has struggled to find the right girl.
"I had two of the greatest girlfriends of all time," Gosling told The Huffington Post. "I haven't met anybody who could top them."
The Blue Valentine star attributed the breakdown of his two main relationships to the pressure of both being in the media spotlight.
"Showbusiness is the bad guy," Gosling explained. "When both people are in showbusiness it's too much showbusiness. It take all of the light, so nothing else can grow."
Gosling recently admitted he wants to have a family sometime in the near future, and would consider giving up acting to become a father.
Drive was released in cinemas this weekend.
> Ryan Gosling - picture special
Watch Ryan Gosling in the trailer for Drive below: