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The 64-year-old Rolling Stones guitarist told the Daily Mail that he is "taking a sabbatical" from his partner after two years together.
"I'm taking a sabbatical from her," he said. "I'm like Picasso, painting up the ladder after leaving his mistress at the bottom after a row."
Friends close to the musician have speculated that their age difference was one of the main reasons for the break-up.
"Ronnie's desperate to remain sober and he found it a real ordeal being dragged along to all these parties with free booze on tap,' a friend told the Daily Star.
"Ana loves going out, but she forgets Ronnie's been partying for 40 years and is happier staying in these days."
Wood previously dated 23-year-old Celebrity Big Brother contestant Ekaterina Ivanova.
> Ronnie Wood 'apologises to ex-wife Jo'










