The Louie star has been selected as the event's feature speaker for the gala, which is "traditionally attended by the President, the Congressional Leadership, media executives, Capitol Hill broadcast journalists and prominent newsmakers".
The dinner's chairman Jay McMichael said he is glad that Louis CK will be a part of one of Washington DC's liveliest events.
McMichael commented in a statement: "We're very excited about having Louis CK at the dinner. This is an evening you'll want to experience. We're shaking things up, showcasing the unexpected, and delivering lots of laughs."
The 68th Annual Radio & Television Congressional Correspondents Dinner will take place on June 8, 2012.
Louis CK writes, directs and stars in the Emmy-nominated FX sitcom Louie. The series was recently renewed for a third season.
> Louis CK returning to Parks and Recreation
> Louis CK to self-release next stand-up show online
Watch a clip from Louis CK's stand-up act below (mature content):