The Wanted singer is flying out to Barbados today to play at the Sandy Lane concert with Rihanna in front of celebrity guests.
George told The Mirror: "We're gonna get him absolutely ragged.
"We'll send our ladies over to chat him up while we slip something into his drink."
George added that his girlfriend, Coronation Street star Michelle Keegan, will be in on the joke.
The 23-year-old added: "Michelle is a good actress, she'll know what to do. I've briefed her."
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Watch The Wanted's video of 'Glad You Came' below: