Jackson claimed on her internet talkshow Politichicks that intelligence sources showed her proof that the US government has been "infiltrated" by the Muslim Brotherhood, a group which played a role in Egypt's revolution earlier this year.
The comic said at her apparently high-level meeting: "I just went to a briefing in Washington DC, across the street from the Capitol, at the Longworth building at 8.30am two days ago and it changed my life…
"For six hours, I saw pictures and names and dates and facts and Islamic law books and Korans, Surahs for six hours and they proved to me... that the Muslim Brotherhood has infiltrated our highest positions in government and this is serious."
Jackson also alleged that US President Barack Obama is secretly a member of the Muslim Brotherhood, declaring: "The Muslim Brotherhood is controlling all of the Middle East... And they are now in all of our highest positions, including the President."
She previously made headlines with a series of critiques of the Fox series Glee for its portrayal of LGBT relationships.
Jackson first accused Glee's producers of "shoving the gay thing down our throats" by showing a gay kiss on an episode and later expressed her belief that "homosexuality is a sin".
The actress first gained fame in a series of Saturday Night Live segments in the 1980s, where she would perform handstands on the 'Weekend Update' desk.
In recent years, she has become a conservative political pundit and a staunch critic of the Obama administration.
Watch Victoria Jackson in a clip from Saturday Night Live below (US only):