The actress took to the stage with her Hot in Cleveland co-stars Valerie Bertinelli, Jane Leeves and Wendie Malick to accept the show's award for 'Favourite Cable TV Comedy'.
Leeves then pointed out that White will turn 90 next week and asked the audience to wish her a happy birthday. The crowd got to its feet and applauded.
"Thank you with all my heart, but you don't really accomplish anything," a moved White told the audience. "90 just happens. I didn't do anything!"
The audience continued clapping in spite of her humble words.
White will celebrate her 90th birthday on January 17, and a television special will air in her honour next Monday (January 16) on NBC.
In December, the actress said she was too busy to retire, insisting that she is having fun working.
More from the People's Choice Awards 2012:
> Nathan Fillion wins 'Favourite TV Drama Actor' at 2012 PCAs
> Jane Lynch blasts Kim Kardashian, Ashton Kutcher at 2012 PCAs
> Nina Dobrev wins 'Favourite TV Drama Actress' at People's Choice Awards
> 'Big Bang Theory' cast open People's Choice Awards 2012
> People's Choice Awards 2012 - The winners
Watch the Hot in Cleveland cast accepting their People's Choice Award below:
Browse a gallery of images from the People's Choice Awards below: