The Wanted star revealed that the group had already met the pair, and said he is "delighted" for One Direction star Styles.
George told Now: "We've met them a few times - they're nice. I'd like to see what they're like after having a beer.
"Harry Styles is doing alright with Caroline Flack, isn't he? I'm delighted for the boy. I think it's great for both of them."
Playing down their controversial age gap, he added: "She's like, 'So what if he's 15 years younger?' and he's like, 'Brilliant, she's 15 years older!'"
Rebecca Ferguson and Kerry Katona have both expressed their disapproval of the romance.
Xtra Factor presenter Flack has already faced an uproar from One Direction fans.
> Caroline Flack: 'Harry Styles relationship isn't disgusting'