The saxophonist's wife has filed a request to LA County Superior Court to legally separate after 20 years of marriage, according to TMZ.
The couple have both apparently hired high-profile lawyers, which could indicate that they are planning to divorce in the coming months.
Benson and the musician are parents to two sons.
Kenny G - real name Kenneth Gorlecki- most recently made headlines for his cameo in Katy Perry's 'Last Friday Night (T.G.I.F.)' music video, playing the uncle of Perry's alter ego Kathy Beth Terry. The clip also featured Hanson and Rebecca Black.
He also recently collaborated with Indian vocalist Rahul Sharma on the album Namaste India.
Watch Kenny G in the 'Last Friday Night (T.G.I.F.)' music video below: