The rapper-actor discussed the current US political scene in a recent interview with The AP, when he predicted that Clinton will run for the presidency in four years.
"She did the Secretary of State job, she was a G, she held it down, she didn't cry," Ice-T commented.
He went on to say: "Obama will support [Clinton] and she'll be the first woman president."
Clinton has claimed that she will likely step down as US Secretary of State if Obama is re-elected in the fall.
Ice-T is the director of the documentary Something From Nothing: The Art of Rap, which was screened at the Sundance Film Festival this week.
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Watch a trailer for Something From Nothing: The Art of Rap below (contains strong language):