The Resident Evil star is featured in the new ad campaign for Avon's City Rush for Her fragrance, reports the Daily Mail.
Jovovich shot the campaign on the streets of New York with male model Carlos Casia Grande.
"I am so excited to be working with Avon as the face of their new fragrance," she said.
"It is a sophisticated fragrance that captures the natural mystery and sensuality of a woman."
City Rush for Her will be released in October.
Jovovich will reprise her role in the zombie saga Resident Evil: Retribution, scheduled to be released on September 14 in the US and September 28 in the UK.
Watch the trailer for Resident Evil: Retribution below: