Suleman came into the public eye after giving birth to octuplets in 2009. She now has a total of 14 children.
The 36-year-old recently filed for bankruptcy with over $1m (£650,000) debt, prompting her to star in a "sex education" film for an undisclosed amount of money.
Sources told TMZ that she will debut as a stripper in scheduled shows at T's Lounge in West Palm Beach, Florida.
Friends say the mother decided to try stripping after being "sexually liberated" since filming her sex education film, which is expected to release later this summer.
T's Lounge is apparently an all-nude bar, although sources say Suleman will only go topless and will not do lap dances.
Suleman will be performing at T's Lounge from July 11 to July 15.