The Rock of Ages star was named master of ceremonies for a live event featuring the Buddhist leader at Manchester's MEN arena on Saturday (June 16).
Despite his past examples of scandalous behaviour, Brand insisted that he has a "genuine respect" for the Dalai Lama and is not out to cause controversy at the talk.
Speaking in an interview with Neil Fox on Magic 105.4, Brand admitted: "I've made mistakes in the past Foxy, I won't lie to you but this one I'm on my game. I'm going to crack on. I'm going to give the Dalai Lama the best show! I'm going to behave.
"He's a holy man, it's not pretend authority, it's proper authority of God... I've got to be entirely respectful of his holiness and that's going to be no problem because I'll tell you why, genuine respect.
"[It's] not like when you're at school and you have to pretend, 'I better pretend that I care what these people are saying', for ten years or however long it is they have you in that crap hole."
Brand recently joked that he should be knighted by The Queen, "otherwise the people will revolt".
Picture Gallery - The Rock of Ages UK premiere: