The America's Got Talent judge was in tears as she addressed son Jack Osbourne's recent diagnosis of multiple sclerosis.
Jack, 26, learned of his illness just weeks after the birth of his baby daughter Pearl Clementine.
"[Jack's] doing really, really good and I want to thank everyone for all their texts and goodwill and love they send to us," Sharon said between sobs. "It's been amazing for Jack because I really believe that... prayer really helps."
The 59-year-old also revealed that son Jack will appear on the show on Wednesday (June 20) to discuss his diagnosis.
She added: "And what I'm doing right now is not helping because I'm just feeling sorry for myself, and that is no good."
Watch Sharon Osbourne's message on The Talk below: