The comedian made the comments on Conan O'Brien's chatshow, claiming that Brits are "too clumsy" to match previous host China.
"I think we are under a lot of pressure, because China were clearly able to demonstrate in the opening ceremony that 'we can make all these people do the exact same thing at once - don't you dare get in a war with us'," Brand said.
Asked if he thinks London will do a good job of hosting the Olympics, he continued: "No way. China did such a great job. We are too clumsy, we are too self effacing - as you know with the English the politeness masks deep sexual deviance.
"I love England, I'm from there. But something that involves organisation is going to be a right balls-up. Things will catch fire and people will be tripping over things, then it'll start raining and the Queen will do a fart."
Brand recently insisted that he is "happier than ever", despite going through a divorce from Katy Perry.
Watch Russell Brand discuss the Olympics on Conan below: