Speaking to Vogue, the Amazing Spider-Man actress explained that she struggled with a number of issues as a youngster, and that acting had been a way to deal with her problems.
"I had a panic attack when I was eight," she said.
"My mum couldn't put notes in my lunch because I would be reminded that she existed and I would want to go home. And I was sick all the time.
"When I went through therapy, I tried improv for the first time, and I think there was some cathartic element to it."
Despite her increasing success, Stone revealed that she is scared of being recognised.
"I worry about my fame making New York unliveable. To not walk around would be awful... that idea makes me physically ill," Stone added.
Stone has recently been promoting the latest reboot of the Spider-Man franchise, alongside boyfriend Andrew Garfield.
Watch the trailer for The Amazing Spider-Man below: