The 30-year-old performer reflected on her admiration for the First Lady in the new video, describing her as "the ultimate example of a truly strong African-American woman".
She goes on to add: "She is a caring mother, she's a loving wife, while at the same time, she is the First Lady."
Beyoncé has been a long-time supporter of Michelle Obama, shooting a special video for her childhood fitness campaign at a New York school last year.
Michelle has also revealed her respect for the 'Countdown' singer, recently admitting: "I wish I was Beyoncé."
Watch Beyoncé in the full campaign ad below: