The 'Like You' rapper complained of discrimination from staff at the Park Plaza hotel in Westminster, where hotel personnel accused him of smoking in his suite.
According to WENN, management visited Bow Wow's hotel room in the early hours of Thursday (July 19) to make the allegations.
The 25-year-old took to his Twitter page to blast the hotel, writing: "The Park plaza westminster hotel sucks. Dont ever stay there. They racist. All these people smoking cigs on my floor and they single me out… they woke me up out my sleep n all… Kept knockn on my door. (sic)"
Bow Wow said that he checked out of the hotel after the accusations, telling another Twitter user: "i moved i dont like problems im too calm & cool for a argument."
This is apparently not the first trouble the rapper-turned-actor has had at the hotel.
He wrote: "I had a problem w/this spot last time i was here they was hatin hard saying video game was too loud n all that."
Bow Wow recently lost a $4,000 (£2,500) limo lawsuit following a dispute with a driving company.