The chat show host recorded a special four-minute opening for the Friday (July 20) broadcast of his show, in which he explained that he decided against showing his original monologue, which was primarily about The Dark Knight Rises.
He said: "Obviously the events of today would make it very difficult for me to broadcast a show tonight which began with the phrase 'It's a great day for America'. I couldn't allow that to happen."
Ferguson goes on to explain that as the monologue was prerecorded the night before the tragedy occurred, it would be in poor taste to air it.
According to Entertainment Weekly, other late night talkshow hosts opted to handle the recent shooting differently, with Jay Leno prefacing his opening monologue with brief words about the incident, adding that "his job was to make people laugh".
Jimmy Fallon chose not to address the issue at all, while Jimmy Kimmel and David Letterman both aired scheduled reruns.
Watch Craig Ferguson's message regarding the Aurora shooting below: