The 36-year-old actress, who will marry fellow soap star Jamie Lomas in September, was spotted at Manchester airport alongside her mother and friends getting ready for the holiday.
The Coronation Street star took to Twitter before take-off to let fans know about her excited mood. She wrote: "What an amazing day!!!! Have a great Friday guys! The weekend starts here! X"
Marsh appeared to have made sure her wedding plans were organised before heading away to southern Spain. On Monday, she tweeted: "Wedding rings..... Check! x"
The couple will marry at the Nunsmere Hall Hotel, Cheshire in September.
> Kym Marsh, Jamie Lomas wedding confirmed for September
> Corrie's Kym Marsh: Michelle "wants to kill" drug addict son