Stars took to Twitter to to praise the director's three-hour celebration of British culture and achievements.
Joe Jonas tweeted throughout the ceremony and revealed that he is a big Mr Bean fan, posting "Mr. Bean was so amazing!"
The BBC's Clare Balding also noted that the skit was bound to be a hit with former hosts China, where Rowan Atkinson's character is "absolutely huge".
The Queen's appearance alongside Daniel Craig's James Bond was a popular moment with celebrities. David Walliams described it as the "best thing [he'd] ever seen" and Joss Stone added: "Love when the queen sky dives from the helicopter, shes much braver than I!".
Former Lost and Lord of the Rings actor Dominic Monaghan also cheekily joked: "I do hope the queen wasn't subjected to the usual Bond girl routine at the hands of James. Not sure the bones could take it."
Victoria Beckham supported her husband's involvement Thames-side, tweeting "So proud to be British" along with a picture of Tower Bridge and the Olympic rings, whereas Ringo Starr sent well wishes to athletes and former bandmate Paul McCartney from Los Angeles.
Some US celebrities were left puzzled by Boyle's quirky references, with Christina Applegate tweeting: "Enjoying the opening ceremony, Danny Boyle, u r (sic) one strange fellow", but other non-Brits got caught up in the moment, including Kylie Minogue and Bette Midler, who enthused: "Wow! What a great nght (sic) for UK; l loved every minute!"
Stars in attendance at the ceremony included Nicole Kidman, Orlando Bloom and girl band Mutya Keisha Siobhan.
Boyle also tweeted after the conclusion of the ceremony, thanking everyone for their support.
"Thank you, everyone, for your kind words! Means the world to me. #London2012," he wrote. "I just want to take a moment to thank everyone involved tonight," he later added. "Couldn't have worked without you. Thank you, thank you so much."
Watch the introduction to the London 2012 Olympics Opening Ceremony below:
Photo gallery - London 2012 Olympics Opening Ceremony:
Copyright: PA Images Anthony Devlin/PA Wire