The Transformers: Dark of the Moon actress, who is currently dating Jason Statham, said she is looking forward to starting a family and becoming less "self-indulgent".
"I always see myself working, but definitely being a mum will be a big part of me," she told Elle. "I think my career is very self-indulgent, it's all about me.
"I'm not a doctor, I'm not looking after people, I'm not saving children. I'm in the entertainment business. I'm a model. I'm an actress.
"So it is very self-involved and I think there is naturally a point where you think, 'I don't care about myself as number one anymore'. I want to care about other things."
The Victoria's Secret star also recalled the tough days at the beginning of her modelling career and lamented the lack of individuality in the fashion industry.
"'I grew up very unaware of my body and how I look; that wasn't something anybody thought about," she said.
"There was no individuality, no opportunity to be individuals. I think that people forget you're human and you just become an object."
Huntington-Whiteley's full interview appears in the September issue of Elle, on sale Wednesday, August 1. It is also available in a digital edition.