The Twilight couple's romance has dominated the media over the last week given Stewart's confirmation that she cheated on Pattinson with married director Rupert Sanders.
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Ferrell has now made light of the serious press coverage that Stewart and Pattinson's love life is receiving in the wake of the scandal.
"I worked it into conversation today on [MSNBC news programme] Morning Joe. Do you realise what's going on? K-Stew cheated on him! And he moved out! It's over! I love how much attention that's getting," the actor quipped, reports USA Today.
The Campaign star also admitted he is reluctant to call Stewart and Pattinson by the popular coupling nickname 'RobSten'.
"I'm going with 'Trampire' right now," he quipped. "I don't care what's going on in Syria. This is what we need to talk about!"
Rapper Professor Green also recently weighed in on the controversy by branding Stewart "a cheating sl*tbag".
Watch Will Ferrell discuss Kristen Stewart's affair on Morning Joe below:
