Osbourne compared her little toe to a sloth and explained that while it used to be one of her insecurities, she has now learnt to embrace her flaws.
Osbourne told Glamour magazine: "You have to look at what you have, the tiniest things, especially since it's the little things that bring you down.
"I used to get picked on because I don't have a baby toenail. It's the weirdest thing, it kind of looks like a sloth, my baby toe.
"But I just take a moment to look at myself and I'm like, 'Wow, I actually have an alright nose. And people don't realise that underneath my little bit of fat, I actually do have abs. So that's alright."
Osbourne, whose parents are Ozzy and Sharon Osbourne, has recently considered that one of the main reasons that she is currently so happy is because she has recognised that she will never be "cool".
"I feel good in my own skin because I've accepted the fact that I'm me," she explained. "That's what's so great about being alive and being on this planet; everybody's different."