The One Direction singer reassured his Twitter followers that he was fine after he was hospitalised with the injury.
He was photographed in crutches in Los Angeles on Friday (September 7), after he was hurt at the MTV Video Music Awards the night before.
Malik reportedly sprained his ankle during the celebrations of the band's three wins at the ceremony.
One Direction fans made 'Get Well Soon Zayn' a worldwide trending topic on Twitter on Sunday.
He wrote: "Hey guys, just to let you all know I'm all good, no need to worry… Just wanna take a moment to thank you guys for being so amazing.
"I've said it so many times but I'll say it again, you really are the best fans in the world… thank you for being so incredible. Love you all."
Malik briefly quit Twitter last month after he complained of too much "hate" on the site, but later returned.