The rapper deleted all of his messages from the social networking site yesterday (October 4).
However, he left one tweet for his followers, saying just: "BE BACK SOON."
West has 8.6m followers on Twitter, but he is currently following only one person - his girlfriend Kim Kardashian.
West is thought to be working on a follow-up to G.O.O.D. Music's recent album Cruel Summer, Cruel Winter.
He recently threatened to take legal action after reports that two sex tapes featuring him were being shopped to various publications.