The couple tied the knot on Saturday (October 6) at their home in Croton-on-Hudson, New York, reports E! .
McDonald, a four-time Tony Award winner, starred in ABC's Private Practice.
Swenson, an actor and director, is best known for his work on Broadway productions such as Hair and Miss Saigon.
McDonald and Swenson met in 2007 when they starred together in the Broadway revival of 110 in the Shade.
The started dating in 2010 and got engaged early this year.
McDonald has a daughter with her former husband, while Swenson has two sons from his former wife.
Watch a promo for Private Practice's sixth season below: