The This Morning host posed for The Hunger magazine's third issue in an east London studio.
Willoughby is seen dressed in leather, stockings and Christian Louboutin shoes, and striking seductive poses in a teaser video for the interview, which is out on October 15.
She recently admitted to being "obsessed" with Marilyn Monroe.
"I'd go back in history and say, 'Right Marilyn, let's sit down, have a glass of champagne and I'll try on your wardrobe. Oh, and did you really have an affair with the president?'" she said.
Willoughby is also unsure of whether she will return to present The Voice UK next year.
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