The bears play a message recorded by the stars when you squeeze their tummy, and money raised via the auction will be used to help young cancer patients.
JLS stars Marvin Humes, Aston Merrygold, Jonathan 'JB' Gill and Oritsé Williams have also recorded individual messages for the campaign.
They are joined by Ed Sheeran, Ricky Gervais, Graham Norton, Dermot O'Leary, Tess Daly, Robbie Savage, Cliff Richard, Cilla Black, Steven Gerrard and others.
Bidding is open now and closes on Sunday, October 28 at 7.40pm via the CLIC Sargent eBay store.
CLIC Sargent head of retail Jeremy Lune said: "The CLIC Sargent 'Care with a Bear' campaign is a fantastic opportunity for die-hard fans to claim a unique, one-off collectible of their favourite British celebrity's voice, which they can listen to whilst cuddling, as the winter nights set in.
"I have no doubt that eBay users will flock to our online shop in a bid to ensure they claim the keepsake that is surely one of the bare essentials to any dedicated fans collection of memorabilia."
He added: "I would like to take this opportunity to thank all of the celebrities who were kind enough to help with the project and offer special appreciation to TV actress Joanna Taylor who helped make the project a success.
"Without their support we wouldn't be able to offer the level of support we do to young cancer patients and their families."