The singer, who had a mastectomy in 2010, announced last month that her breast cancer has returned and has now spread to other parts of her body, leading to doctors diagnosing it as incurable.
However, Nolan has vowed to stay positive in her attempt to fight the disease off for a second time.
In an interview with Hello magazine, the 52-year-old said: "There's no point dwelling on it, I've got to fight it, be positive and get on with it. I say a positive mantra to myself every day."
She also revealed details about the new cancer treatment, adding: "There's a new drug coming out in January called T-DM1 and that's supposed to be revolutionary."
The Nolans have cancelled their upcoming comeback tour while she undergoes treatment.
Steve Doneathy, Nolan's husband of 16 years, was interviewed alongside his wife and spoke of his frustration at the recent diagnosis.
"I still get very angry," he stated. "You do think, 'Why us?' But what can you get furious at? It's an anger that you don't know what to do with.
"I can have my own private thoughts when I'm alone and scared... Bernie is brilliant."
Nolan previously overcame breast cancer after being diagnosed with the disease in 2010.
After being given the all-clear, she recalled of the struggle: "Very quickly I took on a really positive attitude. I thought, 'There's no way I'm going to die from this'. Once you make that decision, you can get on with beating it'."